Using niacin for drug test

Added: Feather Deshazo - Date: 21.12.2021 05:37 - Views: 39657 - Clicks: 4736

Objectives: To report a case of hepatotoxicity when niacin was used by a patient with HIV to pass a drug test. Methods: Niacin is a soluble pyridine derivative widely used in the management of dyslipidemia.

Using niacin for drug test

Common adverse effects include flushing, nausea, gastrointestinal discomfort, and hepatotoxicity. The use of niacin for nonmedical purposes has been increasing in prevalence in recent years, particularly in attempts to alter or mask of urine drug tests. Although there is no scientific evidence that niacin can alter a urine drug screen result, easily retrievable information exists on the Internet touting niacin as a potential way to prevent detection of tetrahydrocannabinol THC. The following report Using niacin for drug test a case of hepatotoxicity in an HIV-infected adult who reported using niacin to mask THC in urine drug Using niacin for drug test.

: The patient developed marked elevations in his liver enzymes aspartate aminotransferase greater than 25 times the upper limit of normal and alanine aminotransferase greater than 3 times the upper limit of normal that resolved after discontinuation of the drug. Because of the patient's self-reported use and discontinuation of niacin, the Naranjo Adverse Drug Reaction Probability Scale demonstrated a "definite" relationship between the development of hepatotoxicity and the ingestion of over-the-counter sustained-release niacin. The patient did not develop further clinical abnormalities proposed to be secondary to niacin toxicity in ly published case reports, including glucose abnormalities, coagulopathies, metabolic acidosis, QTc prolongation, and myalgias.

Conclusion: Health care providers should be aware of this nonmedical use of niacin to alter or mask a drug test, especially when discerning the cause of hepatotoxicity. In addition, pharmacists in the community setting should be aware of this use of niacin when encountering patients purchasing over-the-counter niacin, particularly in patients who may be more likely to use illicit substances. Published by Elsevier Inc. All rights reserved. Please enable it to take advantage of the complete set of features!

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Using niacin for drug test

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Using niacin for drug test

RSS Link Copy. Full text links Cite Display options Display options. Abstract Objectives: To report a case of hepatotoxicity when niacin was used by a patient with HIV to pass a drug test. Similar articles Use of niacin in attempts to defeat urine drug testing--five states, January-September PMID: Metabolic acidosis, hypoglycemia, and severe myalgias: an attempt to mask urine drug screen. Arcinegas-Rodriguez S, et al.

Pediatr Emerg Care. Hepatotoxicity associated with sustained-release niacin. Dalton TA, et al. Am J Med. Hepatic toxicity of unmodified and time-release preparations of niacin. Rader JI, et al. PMID: Review. A Using niacin for drug test review on evidence of the effectiveness and safety of a wax-matrix niacin formulation. Dunatchik AP, et al. J Clin Lipidol. Epub Jul See all similar articles. Publication types Case Reports Actions. MeSH terms Adult Actions. Humans Actions.

Male Actions. Substances Niacin Actions. Full text links [x] Elsevier Science. Copy Download.

Using niacin for drug test

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Toxicity from the use of niacin to beat urine drug screening